Renal Cell Carcinoma Metastases 11 Years After Surgery

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Renal Cell Carcinoma Metastases

Isolated splenic metastases of renal cell carcinoma

A 48-year-old male patient presented to the hospital with a 4-month history of intermittent pain in the left flank. The patient also complained of nausea with the pain. Doctors diagnosed the patient with isolated splenic metastases from renal carcinoma.

Physical examination showed mild discomfort in the upper abdomen. The rest of the examination was normal. Laboratory findings were within normal limits. The patient had a history of renal carcinoma, diagnosed 11 years ago for which the patient underwent left nephrectomy. Findings showed that the renal cell carcinoma had infiltrated beyond the renal capsule, however, was contained within the Gerota’s fascia. Pathological evaluation showed a subtype of clear cell renal cell carcinoma. The patient’s history was also notable for B-cell non-Hodgkin lymphoma which was which was treated surgically and with radiotherapy.

The patient was advised computed tomography (CT) with intravenous contrast for further evaluation.

CT was remarkable, demonstrating two heterogenous hypovascular splenic masses with necrotic areas in the posteroinferior portion. The lesion was seen extending from the splenic capsule to the left diaphragm. The mass measured 4.5 cm and 5.8 cm.

Treatment included splenectomy. Pathology showed that the spleen had two yellowish lesions that measured 6 cm. In addition to this, focal involvement of the diaphragm, angiolymphatic invasion and tumoural necrosis were also observed. The patient showed a complete resolution of symptoms 3 months after surgery and was in good overall health.

References

Isolated Splenic Metastases from Renal Cell Carcinoma 11 Years after Surgery https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778928/

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Dr. Aiman Shahab is a dentist with a bachelor’s degree from Dow University of Health Sciences. She is an experienced freelance writer with a demonstrated history of working in the health industry. Skilled in general dentistry, she is currently working as an associate dentist at a private dental clinic in Karachi, freelance content writer and as a part time science instructor with Little Medical School. She has also been an ambassador for PDC in the past from the year 2016 – 2018, and her responsibilities included acting as a representative and volunteer for PDC with an intention to make the dental community of Pakistan more connected and to work for benefiting the underprivileged. When she’s not working, you’ll either find her reading or aimlessly walking around for the sake of exploring. Her future plans include getting a master’s degree in maxillofacial and oral surgery, settled in a metropolitan city of North America.

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