- Any deviation in the normal colour of urine is an alarming concern for clinicians.
- Urine is frequently observed to be dark yellow to orange, red-brown, brown, yellow or orange.
- This article highlights the case of a patient whose urine became green after five days of admission in the ICU.
A 62-year-old male patient presented to the emergency with complaint of a 2-day history of dyspnea. The patient’s medical history revealed that he had chronic obstructive pulmonary disease and was found to have hypercapnic respiratory failure. اربح المال من الالعاب In addition, the patient’s urine became green five days after admission to the ICU.
On admission, the patient was intubated and mechanical ventilation with continuous infusion of propofol was initiated. The patient was admitted to the intensive care unit. لعبه البوكر لعبه البوكر Five days after the patient was admitted his urine became green, which became a cause of concern.
Green discolouration of urine can be caused because of a number of different factors, for example, infection with pseudomonas species, obstructive jaundice and certain medications including methylene blue, cimetidine, amitryptyline and indomethacin. Laboratory tests showed normal serum total bilirubin levels with no signs of infection. The patient was not taking any medication other than propofol and could have accounted for the urine discolouration.
The colour of the patient’s urine returned to normal after the propofol was discontinued. مواقع المراهنات الرياضية The patient was discharged and referred to a rehabilitation facility after being hospitalised for 2 weeks.
Propofol is metabolized primarily in the liver; it is thought that its phenolic metabolites can cause green discoloration of the urine when it is eliminated through the kidneys. The metabolites are not nephrotoxic, and propofol-induced discolouration of the urine is a benign and uncommon phenomenon.
Green urine due to propofol
Propofol is primarily metabolised and conjugated in the liver and predominantly excreted in the urine as phenolic metabolites. The presence of the phenolic metabolites is believed to be attributed to the discolouration of urine. The discolouration occurs when the propofol eliminated through the hepatic route exceeds, causing extrahepatic elimination. Therefore, discolouration of urine is usually present in patients with prolonged infusion of propofol.
References
Green Urine https://www.nejm.org/doi/full/10.1056/NEJMicm2017137
