30-year-old with 1-month history of rash on face, hands and feet
Despite the high efficacy of penicillin, syphilis still remains a widespread millennial disease. However, before the discovery of penicillin, syphilis claimed many lives, with neurosyphilis being the most fearful complication. اربح The infection is caused by Treponema pallidum and is primarily transmitted via sexual contact. The second most common route of transmission in underdeveloped societies is across the placenta. After the discovery of penicillin, the disease almost disappeared from all corners of the world. However, cases of syphilis are still reported but rarely. And in most cases the condition mimics other dermatological diseases, posing a difficulty for clinical diagnosis. العاب بوكر
Case study: circinate syphilitic lesions
This article describes the case of a 30-year-old with complaints of a 1-month history of rash on his face, hands and feet. The patient’s medical history was consistent with human immunodeficiency virus infection. The patient’s most recent CD4 + T-cell count 374 per cubic millimeter. On further questioning, the patient reported that he had had unprotected sexual intercourse 2 months ago. Physical examination revealed circinate, concentric syphilic lesions on the palms and soles. There were several circinate lesions visible on the patient’s face, with signs of erosion at the oral commissures. العاب تربح فلوس Condyloma latum was evident in the perianal area. Other signs included patchy alopecia on the scalp. Doctors advised a Venereal Disease Research Laboratory (VDRL) test, a screening test for detecting syphilis. The test of the result was positive, confirming the diagnosis of syphilis.
Tests for other sexually transmitted diseases were negative. Doctors treated the patient with intramuscular benzathine penicillin. 1-month after initiating of treatment, the lesions showed complete resolution. Clinicians believe that patients should be screened for syphilis and serologically when you don’t know what it is. Although circinate syphilitic lesions are rare, they are a diagnostic possibility.
Source: NEJM
