Giant Congenital Melanocytic Nevus

Giant Congenital Melanocytic Nevus
  • Giant congenital melanocytic nevi are benign tumours present at birth and consist of melanocytic cells.
  • The cells are found in the epidermis, dermis or other tissues.
  • Garment-like giant congenital melanocytic nevi are very rare and treatment primarily includes excision and split-thickness skin transplantation.

In this case, a 1.5-year-old boy reported to the hospital with a giant nevus. The patient’s birth was normal, however, he developed a very large giant congenital melanocytic nevus of the back (GCMN) immediately after delivery. The GCMN covered about 16% of his total body surface area with multiple smaller nevi on the body.

The patient also complained of severe itching and difficulty with everyday activities. He even had trouble sleeping because of the large tumour on his back.

He was advised a two-stage operation to excise the tumour, based on his complaints. Moreover, coverage with Integra and a split-thickness skin transplantation of 100% vascularised Integra 3 weeks after the excision of tumour. The split-thickness skin transplantation was harvested with a 0.008-inch thickness, meshed 1:1.5. It was fixed at 80 mm Hg with a vacuum-assisted closure technique.

Although, the split-thickness skin transplant was harvested including these lesions because of multiple smaller nevi on the rest of the body. 5 days after the bandage was removed and 90% of the transplant had healed. The defect showed complete healing 2 months after the primary operation and a secondary split-thickness graft .

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2-month postoperative result


Extraordinary Large Giant Congenital Melanocytic Nevus Treated with Integra Dermal Regeneration Template

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Dr. Aiman Shahab is a dentist with a bachelor’s degree from Dow University of Health Sciences. She is an experienced freelance writer with a demonstrated history of working in the health industry. Skilled in general dentistry, she is currently working as an associate dentist at a private dental clinic in Karachi, freelance content writer and as a part time science instructor with Little Medical School. She has also been an ambassador for PDC in the past from the year 2016 – 2018, and her responsibilities included acting as a representative and volunteer for PDC with an intention to make the dental community of Pakistan more connected and to work for benefiting the underprivileged. When she’s not working, you’ll either find her reading or aimlessly walking around for the sake of exploring. Her future plans include getting a master’s degree in maxillofacial and oral surgery, settled in a metropolitan city of North America.


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