Full-Thickness Retinal Detachment

Retinal corrugations radiating from the fovea and normal vasculature (Panel A). Optical coherence tomography revealed a full-thickness retinal detachment and corrugation of deep layers of the retina (Panel B, arrows)

A 19-year-old boy with X-linked retinoschisis presented with worsening of vision in his right eye. On examination, diffuse retinochosis, corrugation of deep layers of retina and full-thickness retinal detachment was revealed.

A 19-year-old male patient presented to the clinic with his vision worsening in his right eye. According to him, his vision had started worsening 3 days ago. He had been diagnosed with X-linked retinoschisis at 5 years of age. At the time of diagnosis, macular cystic degeneration and reduced visual acuity in both eyes had also been noted.

X-linked retinoschisis

X-linked retinoschisis is a condition that affects the retina. It begins in childhood and is characterised by impaired vision. The disorder almost exclusively occurs in males.

The visual acuity of the patient in the right eye was 20/70 and in the left eye was 20/40. In addition, examination of the right fundus showed prominent retinal corrugation that radiated from the normal vasculature and fovea. Optical coherence tomography showed diffuse retinoschisis, corrugation of the deep layers of retina and full-thickness retinal detachment.

However, the patient was treated non-surgically since no retinal tears were observed. The patient was prescribed a 2-week course of daily oral acetazolamide. The retinal detachment resolved after completion of the course of medication. The visual acuity of the patient returned to a baseline of 20/40 in follow-up in both eyes.


Lee, Y., & Oh, B. L. (2020). Retinal Detachment in X-Linked Retinoschisis. The New England Journal of Medicine382(12), 1149-1149.

Previous articlePenile Kaposi’s Sarcoma In HIV Patient
Next articleCannabis Exposure in the Womb
Dr. Aiman Shahab is a dentist with a bachelor’s degree from Dow University of Health Sciences. She is an experienced freelance writer with a demonstrated history of working in the health industry. Skilled in general dentistry, she is currently working as an associate dentist at a private dental clinic in Karachi, freelance content writer and as a part time science instructor with Little Medical School. She has also been an ambassador for PDC in the past from the year 2016 – 2018, and her responsibilities included acting as a representative and volunteer for PDC with an intention to make the dental community of Pakistan more connected and to work for benefiting the underprivileged. When she’s not working, you’ll either find her reading or aimlessly walking around for the sake of exploring. Her future plans include getting a master’s degree in maxillofacial and oral surgery, settled in a metropolitan city of North America.


Please enter your comment!
Please enter your name here